AR, androgen receptor, 367

N. diseases: 854; N. variants: 163
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 GeneticVariation group LHGDN Polymorphic CAG repeats in the androgen receptor gene, prostate-specific antigen polymorphism and prostate cancer risk. 12376473 2002
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 AlteredExpression group LHGDN AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR. 12482965 2003
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 AlteredExpression group LHGDN Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways. 11751884 2002
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker group LHGDN Regulation of androgen receptor transcriptional activity by rapamycin in prostate cancer cell proliferation and survival. 18776922 2008
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 GeneticVariation group LHGDN Polymorphisms in genes regulating androgen activity among prostate cancer low-risk Inuit men and high-risk Scandinavians. 17376218 2008
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Therapeutic group CTD_human Antiandrogen bicalutamide promotes tumor growth in a novel androgen-dependent prostate cancer xenograft model derived from a bicalutamide-treated patient. 16266977 2005
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker group CTD_human Successful Treatment of Advanced Metastatic Prostate Cancer following Chemotherapy Based on Molecular Profiling. 22666205 2012
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker group LHGDN Androgen receptor signaling and vitamin D receptor action in prostate cancer cells. 15754350 2005
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker group CTD_human Cellular changes in prostate cancer cells induced by intermittent androgen suppression. 17141945 2007
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Therapeutic group CTD_human Endocrine approaches in the therapy of prostate carcinoma. 15790600 2005
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 AlteredExpression group BEFREE Flow cytometric analysis of androgen receptor expression in human prostate tumors and benign tissues. 10815917 2000
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 AlteredExpression group LHGDN Glyceraldehyde-3-phosphate dehydrogenase enhances transcriptional activity of androgen receptor in prostate cancer cells. 17553795 2007
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker group LHGDN Hinokitiol, a metal chelator derived from natural plants, suppresses cell growth and disrupts androgen receptor signaling in prostate carcinoma cell lines. 17055455 2006
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 AlteredExpression group BEFREE Two thirds of prostate tumors retained high levels of ZNF652 (71/109 cases) and 50% of tumors high levels of AR (57/113). 20204290 2010
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker group CTD_human Endocrine approaches in the therapy of prostate carcinoma. 15790600 2005
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Therapeutic group CTD_human Successful Treatment of Advanced Metastatic Prostate Cancer following Chemotherapy Based on Molecular Profiling. 22666205 2012
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 AlteredExpression group LHGDN Ku is a novel transcriptional recycling coactivator of the androgen receptor in prostate cancer cells. 15640154 2005
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 AlteredExpression group BEFREE Because ARA70 can promote the antiandrogen hydroxyflutamide (HF)-enhanced AR transactivation, the increased ARA70 expression in hormone-refractory prostate tumors may confer the development of HF withdrawal syndrome, commonly diagnosed in patients with the later stages of prostate cancer. 15166229 2004
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker group BEFREE Androgen receptor versus erbB-1 and erbB-2 expression in human prostate neoplasms. 14654929 2004
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Therapeutic group CTD_human Androgen deprivation therapy for prostate cancer: current status and future prospects. 15389811 2004
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker group LHGDN Polymorphic CAG/CAA repeat length in the AIB1/SRC-3 gene and prostate cancer risk: a population-based case-control study. 11927493 2002
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker group BEFREE To identify HOXB13 transcriptional targets in metastatic PCs, we performed integrative bioinformatics analysis of differentially expressed genes (DEGs) in the proximity of the human prostate tumor-specific AR binding sites. 31273254 2019
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 GeneticVariation group BEFREE The coregulatory proteins ARA70 and ARA160 differentially affected the activity of the mutated AR Glu(231)-->Gly, which was discovered in a mouse authochthonous prostate tumor. 12083956 2001
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker group BEFREE In the present study we investigated the effects of this antisense AR ODN on prostate tumor growth in vivo using a mouse xenograft model. 11857028 2002
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 GeneticVariation group LHGDN Glutamine tract length of human androgen receptors affects hormone-dependent and -independent prostate cancer in mice. 17906287 2008